@media screen {
html[data-pi-theme=dark] body.pi-modern{color-scheme:dark;--pi-paper:#080d1b;--pi-panel:#121b30;--pi-ink:#edf2ff;--pi-copy:#becbe1;--pi-muted:#9fafd0;--pi-blue:#8aadff;--pi-violet:#aa77ff;--pi-cyan:#67d7f6;--pi-rule:#2a3854;--pi-soft:#1d2a48;--pi-shadow:0 12px 32px #00000025;background:radial-gradient(ellipse at 90% 0,#4a23731b,transparent 40%),#080d1b;color:var(--pi-copy)}
html[data-pi-theme=dark] body .header{background:#0b1224!important;border-bottom:1px solid #26324c;box-shadow:0 5px 28px #0003}
html[data-pi-theme=dark] body .conceptbar{background:#080e1d;color:#9caecc;border-color:#24314d}
html[data-pi-theme=dark] body :is(.pi-discovery-search,.edu-card,.pi-protocol-card,.three-grid>*,.pi-source-toolbar,.wp-library-filter,.pi-next-reading,.pi-board,.pi-comparison,.pi-topic-request,.pi-profile-article,.pi-blog-article,.pi-article-section){background:#121b30;border-color:#2a3854;color:#becbe1;box-shadow:0 12px 32px #0002}
html[data-pi-theme=dark] body .pi-discovery-search{background:radial-gradient(ellipse at top right,#57339728,transparent 60%),#111a2e}
html[data-pi-theme=dark] body .pi-index-hubs>a:nth-child(n){background:linear-gradient(145deg,#182a4b,#111a2d 70%);border-color:#2e4165;border-top-color:#6594ff;color:#edf2ff!important}
html[data-pi-theme=dark] body .pi-index-hubs>a:nth-child(2){background:linear-gradient(145deg,#2a2045,#131a2e 70%);border-top-color:#ac75ff}
html[data-pi-theme=dark] body .pi-index-hubs>a:nth-child(3){background:linear-gradient(145deg,#14333f,#111a2d 70%);border-top-color:#64cde7}
html[data-pi-theme=dark] body .pi-index-hubs :is(p,ul){color:#b9c8e0}
html[data-pi-theme=dark] body .pi-index-hubs .pi-hub-lead{color:#e1e9fb}
html[data-pi-theme=dark] body .pi-index-hubs .pi-hub-kicker{color:#a8bbdf}
html[data-pi-theme=dark] body .pi-index-hubs .pi-hub-cta{color:#9cb9ff;border-color:#314263}
html[data-pi-theme=dark] body :is(.pi-index-hubs>a,.edu-card,.pi-protocol-card):hover{border-color:#9b7be4;box-shadow:0 10px 30px #784ce31c}
html[data-pi-theme=dark] body input:not([type=checkbox]):not([type=radio]):not([type=submit]),html[data-pi-theme=dark] body :is(select,textarea){background:#0b1222;color:#edf2ff;border-color:#344464;box-shadow:inset 0 2px 5px #0002}
html[data-pi-theme=dark] body input::placeholder{color:#8192b2}
html[data-pi-theme=dark] body :is(.action,.pi-source-more,.pi-source-cta){background:linear-gradient(110deg,#3f65f0,#9452e8);box-shadow:0 5px 20px #714ceb30;color:#fff!important}
html[data-pi-theme=dark] body :is(.hero,.pi-source-hero){background:radial-gradient(ellipse at top right,#8045ce75,transparent 58%),linear-gradient(115deg,#101d48,#173995 65%,#48288f);border:1px solid #405393;box-shadow:0 20px 45px #0003}
html[data-pi-theme=dark] body :is(.hero,.pi-source-hero) .action{background:#f2f4ff;color:#243c87!important}
html[data-pi-theme=dark] body :is(.pi-tool-actions a,.pi-tool-actions button,.pi-result button,.pi-copy-section,.pi-source-jumps a,.pi-compound-routes a){background:#1b2944;color:#b0c8ff;border-color:#33476b}
html[data-pi-theme=dark] body :is(.pill,.pi-evidence-badge,.edu-card small,.pi-protocol-card>span){background:#223152;color:#bccfff}
html[data-pi-theme=dark] body :is(.pi-quick-answer,.pi-toc){background:#18233d;color:#c1cde4;border-color:#a578ed}
html[data-pi-theme=dark] body footer.footer.wrap{background:#090f20;border-top-color:#8853dd}
html[data-pi-theme=dark] body :is(.fine,small){color:#9dadcb}
html[data-pi-theme=dark] body #main-content p{color:#b9c8e0}html[data-pi-theme=dark] body #main-content .pi-hub-lead{color:#e1e9fb}html[data-pi-theme=dark] body #main-content .hero p{color:#e2eaff}html[data-pi-theme=dark] body .pi-discovery-search [role=status]{color:#9fafd0}
html[data-pi-theme=dark] body :is(.pi-article-section>header,.pi-profile-article h2,.pi-blog-article h2){background:linear-gradient(110deg,#1b2946,#24203c);border-color:#354361}
html[data-pi-theme=dark] body :is(.pi-source-context,.pi-label-context,.review-box,.pi-supply-planner,.disclosure){background:#162139;color:#c3cee3;border-color:#344464}
html[data-pi-theme=dark] body .pi-toc{background:#18233d!important}
html[data-pi-theme=dark] body :is(.pi-dose-table table,table){background:#121b30;color:#c3cee3}
html[data-pi-theme=dark] body :is(th,.pi-dose-table th,.pi-protocol-article .pi-dose-table th,#pi-compare-table th){background:#1d2c49;color:#e8efff}
html[data-pi-theme=dark] body :is(td,th,.pi-reference-list>li){border-color:#344464}
html[data-pi-theme=dark] body :is(.pi-source-alphabet button,.pi-source-reset,.page-numbers){background:#182640;color:#c1d4ff;border-color:#35496e}
html[data-pi-theme=dark] body .pi-source-alphabet button[aria-pressed=true]{background:#6950d2;color:#fff}
html[data-pi-theme=dark] body :is(.pi-protocol-facts dt,.pi-source-facts dt){color:#a9bad7}
html[data-pi-theme=dark] body :is(.pi-source-links a,.pi-tool-actions button,.pi-topic-request button){background:#1b2944;color:#b9ceff;border-color:#344464}

}

.pi-theme-toggle{display:flex;gap:3px;align-items:center;flex-shrink:0;padding:4px;background:#edf2ff;border:1px solid #cfdaf1;border-radius:100px}
.pi-theme-toggle button{background:transparent;color:#425779;border:0;border-radius:100px;padding:9px 14px;min-height:40px;font:600 12px Arial,sans-serif;cursor:pointer}
.pi-theme-toggle button[aria-pressed=true]{background:#fff;color:#183b82;box-shadow:0 2px 8px #13214d16}
.pi-theme-toggle button:focus-visible{outline:3px solid #a978f0;outline-offset:3px}
.header .wordmark .pi-logo-dark{display:none}
@media screen {
 html[data-pi-theme=dark] .header .wordmark .pi-logo-light{display:none}
 html[data-pi-theme=dark] .header .wordmark .pi-logo-dark{display:block;filter:none}
 html[data-pi-theme=dark] .pi-theme-toggle{background:#16223b;border-color:#354363}
 html[data-pi-theme=dark] .pi-theme-toggle button{color:#b8c7e2}
 html[data-pi-theme=dark] .pi-theme-toggle button[aria-pressed=true]{background:linear-gradient(110deg,#4368eb,#8c50de);color:#fff}
}
@media(max-width:1100px){.pi-modern .header .header-cta{display:none}}
@media(max-width:600px){.pi-modern .header .pi-theme-toggle{order:0;margin-left:auto}.pi-modern .header nav{order:2;width:100%}.pi-theme-toggle button{padding:7px 10px;min-height:36px}.pi-modern .header{gap:8px!important}.pi-modern .header .wordmark{flex-basis:170px!important;width:170px!important}}
@media print{.pi-theme-toggle{display:none}}